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Pedicle Screw impants treated with Namovis technology

nanoVIS Ti Surface Technology

Advanced Solutions for Titanium Pedicle Screws

Nanovis® is a pioneering surface technology-driven company committed to addressing unmet clinical needs and developing innovative solutions. Their flagship nanoVIS Ti™ Surface Technology is making waves in the spine, orthopedic, and dental industries, particularly for its unique nanotechnology designation with the FDA, aimed at enhancing bone-to-implant osseointegration. Other noted benefits include reducing bacterial colonization when introduced to our nano surface.

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Common Problems Associated with Titanium Pedicle Screws


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Problem: Loosening

The term “aseptic loosening” refers to the loosening of an implant from native bone without infection or trauma complications. Excessive motion where the bone and implant interface causes aseptic loosening. It is one of the most common reasons for implant failure and often results in revision spine surgery. Loosening is enhanced by poor bone quality and pull-out forces created by long fusion constructs (deformity).

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Our Solution

Titanium implants enhanced with nanoVIS Ti™ Surface Technology accelerate osseointegration between the implant surface and bone. With rapid establishment of bone approximated to the implant substrate, micromotion is reduced, substantially lessening the chance of aseptic loosening.

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Problem: Loosening

Titanium implants enhanced with nanoVIS Ti™ Surface Technology accelerate osseointegration between the implant surface and bone. With rapid establishment of bone approximated to the implant substrate, micromotion is reduced, substantially lessening the chance of aseptic loosening.

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Our Solution

Titanium implants enhanced with nanoVIS Ti™ Surface Technology accelerate osseointegration between the implant surface and bone. With rapid establishment of bone approximated to the implant substrate, micromotion is reduced, substantially lessening the chance of aseptic loosening.

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Problem: Infection

Implants can fail due to a decline in systemic health, bacterial accumulation or trauma. In cases of bacterial colonization, perioperative contamination is a significant risk factor. Infections cause several problems, including inflammation, that jeopardize pedicle screw stability.

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Our Solution

Titanium implants enhanced with nanoVIS Ti™ Surface Technology catch osteogenic proteins that encourage rapid attachment of mature osteocytes and stem cells. The attached cells are driven to accelerate the calcification of extra cellular matrix, resulting in bone proliferation over the implant surface. Increased occupation of the surface by host bone reduces available surface area for bacterial colonization. Additionally, the accompanying increase in micro vascularization allows the body’s immune system to respond naturally to potential bacterial threats. Managing wound care and supporting spinal fusion procedures with antibiotics can also prevent implant failure due to infection.

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Problem: Infection

Implants can fail due to a decline in systemic health, bacterial accumulation or trauma. In cases of bacterial colonization, perioperative contamination is a significant risk factor. Infections cause several problems, including inflammation, that jeopardize an implant’s stability.

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Our Solution

Titanium implants enhanced with nanoVIS Ti™ Surface Technology catch osteogenic proteins that encourage rapid attachment of mature osteocytes and stem cells. The attached cells are driven to accelerate the calcification of extra cellular matrix, resulting in bone proliferation over the implant surface. Increased occupation of the surface by host bone reduces available surface area for bacterial colonization. Additionally, the accompanying increase in micro vascularization allows the body’s immune system to respond naturally to potential bacterial threats. Managing wound care and supporting spinal fusion procedures with antibiotics can also prevent implant failure due to infection.

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Problem: Implant Longevity

There are many reasons why pedicle screws fail early or long-term, chief among them being poor osseointegration. Proper placement, bone growth, and maintenance of an aseptic environment safeguard the pedicle screw and its longevity in patients.

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Our Solution

nanoVIS Ti™ Surface Technology improves the already excellent lifespan of titanium implants. Its advanced nanotechnology is a permanent surface proven in orthopedic applications to trigger osseointegration of bone-to-implant, reducing the colonization of bacteria. When a properly placed pedicle screw is correctly supported by rapid bone formation, issues that cause pedicle screws to fail are avoided, increasing longevity.

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Problem: Implant Longevity

There are many reasons why pedicle screws fail early or long-term, chief among them being poor osseointegration. Proper placement, bone growth, and maintenance of an aseptic environment safeguard the pedicle screw and its longevity in patients.

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Our Solution

nanoVIS Ti Surface Technology™ improves the already excellent lifespan of titanium implants. Its advanced nanotechnology is a permanent surface proven in orthopedic applications to trigger osseointegration of bone-to-implant, reducing the colonization of bacteria. When a properly placed pedicle screw is correctly supported by rapid bone formation, issues that cause pedicle screws to fail are avoided, increasing longevity.

Decrease implant failure and create better outcomes with nanoVIS Ti™ Surface Technology.

nanoVIS Ti™ Surface Technology At-a-Glance

Nanotechnology Designation with comparative surface data showing Mesenchymal Stem Cell and Osteoblast mineralization, on-label

Nanotechnology Designation with comparative surface data showing Mesenchymal Stem Cell and Osteoblast mineralization, on-label


Faster and more consistent osseointegration coupled with increased micro vascularization reduces bacterial colonization

Faster and more consistent osseointegration coupled with increased micro vascularization reduces bacterial colonization


Multiple 510k clearances and process validations on both CP Ti and Ti alloys

Multiple 510k clearances and process validations on both CP Ti and Ti alloys


ISO 13485:2016 compliant controlled QMS process operated by Nanovis

ISO 13485:2016 compliant controlled QMS process operated by Nanovis


Sales force and surgeon excitement with increased technology pricing and market share wins

Sales force and surgeon excitement with increased technology pricing and market share wins


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Nanovis® is seeking licensing partners in the pedicle screw market.

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