The Four
Pillars of
Nanotechnology
Healing

Nanotechnology is an engineered solution that addresses several overlapping issues. These include bacterial colonization of the implant, inflammation around the implant, vascularization after implantation, and osseointegration. Solutions optimized for one of these problems may not solve others. We focused on innovating nanotechnology to address all four issues in a single approach.

Nanovis has successfully engineered our

nanoVIS Ti™ Surface Technology

to optimize implant integration from implantation to the end goal of osseointegration.

Improves Inflammatory Response

Improves Inflammatory Response

Nanovis' nanotechnology increases protein attachment for a lower immune response. It also decreases inflammatory cell attachment and activation while encouraging pro-healing macrophages.

Reduce Bacterial Colonization

Reduce Bacterial Colonization

Nanovis implants incorporate antimicrobial elements to reduce the risk of infections, a major concern in orthopedic and spinal surgeries.

Increases Vascularization Improves Healing

Increases Vascularization Improves Healing

Our nanotubes speed up vascular growth on the implant, supporting new bone growth and accelerating healing.

Accelerating Osseointegration Stabilizing Implants

Accelerating Osseointegration Stabilizing Implants

Osseointegration is the marker of successful implantation. The sooner bone firmly attaches to the implant, the better the outcome.

Enhance implant

PerformanceOsseointegrationVascularizationInflammatory Response

Focused on our four pillars of healing, Nanovis engineers and produces nano surface technologies to improve the integration of orthopedic, spinal, and dental implants.

Intellectual Property Protection

Nanovis® maintains a robust intellectual property portfolio consisting of several owned or licensed patents. All nanoVIS Ti™ Surface Technology components are protected by a series of patents. Additionally, the proprietary process used to produce our unique surface is safeguarded by multiple trade secrets.

Regulatory Strategy and Pathway

01

NanoVIS Ti™ Surface Technology is the only widely available platform nanotechnology to achieve FDA’s nanotechnology designation.

02

We are the first company worldwide to obtain FDA clearance and nanotechnology designation for a pedicle screw system.

03

We are the second company worldwide to receive FDA clearance and nanotechnology designation for an interbody fusion cage.

04

The Master File for nanoVIS Ti™ Surface Technology has been referenced for multiple 510k clearances across two different product types in spine.

Manufacturing Operations

Image

The application of nanoVIS Ti™ Surface Technology utilizes a validated manufacturing process that can fit within any supply chain. The flexibility of our proprietary process allows for the support of a wide range of quantities, both large and small, in an economical way.

Clinical and Commercial Advantages

To validate the nanoVIS Ti™ Surface Technology, Nanovis® has commercialized a portfolio of spinal products.

Image
Image
Image

Clinical Advantages

01

FDA nanotechnology designation. First company in the world with designation on Peek + Ti Interbodies (CP Ti), and Open and MIS pedicle screws (ELI Ti).

02

Statistically significant and superior comparative surface data in the label – hMSC mineralization and osteoblast mineralization at 21 days, in vitro.

Commercial Benefits

01

On-label marketing for superior positioning and messaging.


02

Superior FDA label used to drive new surgeon conversions, hospital approvals, and technology price premiums.

03

Surface on a surface story. Great way to further enhance/differentiate with a nano surface on a macro-porous 3D printed surface, or a micron roughened surface.

04

Surgeon engagement at a scientific and innovation level creating opportunities for studies, papers, podium presentations, etc.

Commercial Products

Discover our Products at nanovisspine.com
Image
Return to home page